American Association for the Advancement of Science sponsored membership
Sponsored membership, American Association for the Advancement of Science, 2013
2013 - 2015
Sponsored membership, American Association for the Advancement of Science, 2013
2013 - 2015
Scholarship, Monash University, 2019
2019 - 2022
Scholarship, Monash University, 2019
2019 - 2022
Poster prize, Monash University, 2019
2019
Talk prize, Australian National University, Australia, 2019
2020
Published in PeerJ, 2016
The Rohart MSC test is a simple in silico test that accurately discriminates MSC from fibroblasts, other adult stem/progenitor cell types or differentiated stromal cells.
Recommended citation: Florian Rohart, Elizabeth A. Mason, Nicholas Matigian, Rowland Mosbergen, Othmar Korn, Tyrone Chen, Suzanne Butcher, Jatin Patel, Kerry Atkinson, Kiarash Khosrotehrani, Nicholas M. Fisk, Kim-Anh Lê Cao, Christine A. Wells, "A molecular classification of human mesenchymal stromal cells." PeerJ, 2016, 4:e1845. DOI: https://doi.org/10.7717/peerj.1845 https://doi.org/10.7717/peerj.1845
Published in Stem Cells, 2016
This investigation comprehensively characterizes and contrasts human lung derived mesenchymal stromal cells (MSCs) from tissue and bronchoalveolar lavage.
Recommended citation: Kenneth A Sinclair, Stephanie T Yerkovich, Tyrone Chen, Jonathan L McQualter, Peter M-A Hopkins, Christine A Wells, Daniel C Chambers, "Mesenchymal Stromal Cells are Readily Recoverable from Lung Tissue, but not the Alveolar Space, in Healthy Humans" Stem Cells, 2016, 34: 2548-2558. DOI: https://doi.org/10.1002/stem.2419 https://doi.org/10.1002/stem.2419
Published in Nucleic Acids Research, 2018
Stemformatics includes curated ‘collections’ of data relevant to cell reprogramming, as well as hematopoiesis and leukaemia.
Recommended citation: Jarny Choi, Chris M Pacheco, Rowland Mosbergen, Othmar Korn, Tyrone Chen, Isha Nagpal, Steve Englart, Paul W Angel, Christine A Wells, "Stemformatics: visualize and download curated stem cell data." Nucleic Acids Research, Volume 47, Issue D1, 08 January 2019, Pages D841–D846. DOI: https://doi.org/10.1093/nar/gky1064 https://doi.org/10.1093/nar/gky1064
Published in Nature Cell Biology, 2020
We provide evidence for a wave of human T-cell development that originates directly from haemogenic endothelium via a RAG1+ intermediate with multilineage potential.
Recommended citation: Ali Motazedian, Freya F. Bruveris, Santhosh V. Kumar, Jacqueline V. Schiesser, Tyrone Chen, Elizabeth S. Ng, Ann P. Chidgey, Christine A. Wells, Andrew G. Elefanty, Edouard G. Stanley, "Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids." Nat Cell Biol 22, 60–73 (2020). DOI: https://doi.org/10.1038/s41556-019-0445-8 https://rdcu.be/b440v
Published in bioRxiv, 2020
We demonstrate that it is possible to combine a large number of different profiling experiments summarised from dozens of laboratories and representing hundreds of donors, to create an integrated molecular map of human tissue.
Recommended citation: Paul W Angel, Nadia Rajab, Yidi Deng, Chris M Pacheco, Tyrone Chen, Kim-Anh Lê Cao, Jarny Choi, Christine A Wells, "A simple, scalable approach to building a cross-platform transcriptome atlas." bioRxiv, 2020.03.09.984468. DOI: https://doi.org/10.1101/2020.03.09.984468 https://doi.org/10.1101/2020.03.09.984468
Published in GigaScience, 2020
In this review, we perform a critical analysis of methods with the explicit aim of harmonizing data, as opposed to case-specific integration.
Recommended citation: Tyrone Chen, Sonika Tyagi, "Integrative computational epigenomics to build data-driven gene regulation hypotheses." GigaScience, Volume 9, Issue 6, June 2020, giaa064. DOI: https://doi.org/10.1093/gigascience/giaa064 http://dx.doi.org/10.1093/gigascience/giaa064
Published:
Published:
Tutoring, Australian National University, Research School of Biology, 2011
2011
Workshops, Monash University, 2019
2019 - present
Workshops, EMBL Australia, 2019
2019
Workshops, , 2020
2020 - present
Workshops, Monash University, 2020
2020
Workshops, Australian National University (virtual from COVID-19 pandemic of 2019), 2020
2020